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Etizolam side effects

What is Etizolam?

Etizolam is a medicine that is used in Italy, Japan and India for the treatment of anxiety, panic attacks and insomnia.

Within the last few years it has received growing attention online. Etizolam is being sold by online “research chemical” vendors because of its similar effects to Xanax. Unlike benzodiazepine drugs like Xanax or Valium however, Etizolam is not covered by drug legislation in many countries and some states within the USA.  It does not strictly fall under the research chemical status however, as it is a legal medicine with prescription in some countries.

Why do people want to take Etizolam?

Etizolam produces a range of effects that many users find helpful or therapeutic. Etizolam at the correct dose can be used to aid in the passage in to sleep. It also has powerful anxiety reducing qualities.

At recreational doses some report that Etizolam is more “euphoric” than related benzodiazepines such as Xanax (Alprazolam).

It may be used recreationally to aid the comedown from psychedelics or amphetamines like speed or MDMA (Ecstacy).

What are the common side effects?

As Etizolam is a prescribed medicine in some countries, we are fairly well informed of its side effects.

Physical side effects that lie outside of the desired effects include:

  • Loss of energy and motivation
  • Loss of coordination
  • Slowed or depressed breathing
  • Yawning
  • Loss of appetite
  • Nausea and vomiting
  • Dry mouth
  • Involuntary closure of the eyes
  • Lowered heart rate
  • Blurred vision
  • Headache
  • Return of insomnia after a long period of use

Some mental side effects:

  • Loss of memory
  • Loss of inhibition
  • Confusion

The Etizolam “Comedown”

Users report little to no comedown after the main effects of Etizolam have worn off. However, long term continual use over a period of weeks to months can lead to a rebound of the anxiety or sleeplessness that the medication was intended to alleviate.

See Also

Etizolam withdrawal after prolonged continual daily use

Like Xanax or Valium, the experience of withdrawal after a long period of continual use of Etizolam can be particularly hellish.

In fact acute withdrawal from benzodiazepines and “benzodiazepine like” drugs is considered by some to be worse than the withdrawal from opiates like morphine or Oxycodone.

The range of health problems encountered by people withdrawing abruptly from these drugs is known as “benzodiazepine withdrawal syndrome”.

It is characterised by tension, anxiety, sweating, panic attacks, trouble sleeping, confusion, problems concentrating, headache, muscle pain, weight loss and memory problems amongst other effects.

For this reason, many people find themselves using drugs like Etizolam again to avoid these withdrawal effects.

People who use Etizolam over a long time therefore easily become dependent on the drug to function. It is highly physically and psychologically addictive.

Use with alcohol

It is particularly dangerous to use Etizolam with alcohol. This combination vastly increases the likelihood of loss of consciousness and total respiratory depression. Death is known to result from users passing out, vomiting, and then breathing this vomit in to their airways.


Etizolam has a similar side effect profile to more commonly known drugs like Xanax. It is well tolerated if used in small amounts for a short period of time, but there are some truly nasty consequences of long term use that can ruin lives.

The best way to stop using Etizolam after a long period of continual use is to gradual taper down the dose, never halt abruptly.