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flobromazolamFlubromazolam is a highly potent, short-acting derivative of benzodiazepine

Flubromazolam, similar in structure to pyrazolam, flubromazepam and triazolam, is also a derivative of benzodiazepine. It is named after the triazole, bromine, and fluorine on the core skeleton of the benzodiazepine. Benzodiazepine drugs contain a benzene ring and also a diazepine ring. A methylated triazole ring fuses with the diazepine ring at R1 and R2. The bromine binds at R7. The Fluorine binds at R5 to the phenyl ring.


Flubromazolam, C17H12BrFN4, has a molar mass of 371.21 g mol-1 and is illegal in Sweden and Switzerland. Canada regulates the drug as a Schedule IV, whereas it is listed as Schedule I in the state of Virginia, USA. Flubromazolam is highly potent – the ‘threshold dose’ is merely 80 μg (micrograms).

In general, benzodiazepines may have long-term, intermediate, or short-term effects. Note that flubromazolam acts in the short term (18 hours) whereas the chemically similar and nearly eponymous drug flubromazepam acts over a much longer period (4 to 5 days). In some instances they might be used during alcohol withdrawal or prior to minor dental or medical operations. But currently tests of safety for use in humans are lacking.

Flubromazolam is quite potent and long lasting (half-life of 18 hours), possibly more so than other designer drugs, thus there may be a relatively higher, potentially life-threatening risk at low dosages such as 3 mg. Interactions with stimulants, dissociatives, or depressents may substantially increase the risk of usage.

Flubromazolam is highly addictive, both psychologically and physically and users build tolerance quickly (within days). Discontinuing use while tapering is extremely difficult. Overdosing is a major risk, particularly when interacting with other chemicals. It can result in brain injury, coma, or death. Symptoms of overdose include delusions, confusion, slurred speech, respiratory depression, coma or death. Except in cases of death, overdoses of benzodiazepines generally turn out alright if treated effectively in a hospital, though care is mainly supportive.

Cognitive effects include hypnotic feelings, amnesia, compulsive redosing, delusions of sobriety, dream potentiation, deceleration of thoughts, suppression of emotions, suppression of anxiety, suppression of analysis, suppression of information processing, and disinhibition. Physical effects reported by users include diminished motor control, dizziness, relaxation of muscles, sedation, and respiratory depression. Paradoxically, some epileptic users reported experiencing increasing seizures. Others displayed irritability and aggression, lack of control of impulses or violence. A few noticed suicidal ideation or behavior. Such paradoxical effects happen more frequently in individuals on high dosages, in recreational settings, or struggling with mental illness.

Muscle relaxants, sedatives, sleeping pills, anticonvulsants, and anti-anxiety medications all utilize benzodiazepines as active ingredients. Lethargy and feeling deprived of sleep have been reported.

Benzodiazepines produce several effects including amnesia by connecting with a receptor for benzodiazepine, thereby amplifying efficiency of GABA. Modulation causes calmining or sedation and it can also be used against convulsions when bound to sodium channels (which are voltage-dependent). Withdrawing suddenly from benzodiazepines could be dangerous, possibly causing seizures or death, without tapering down the dosage.

See Also:

  • Pyrazolam
  • Psycho active substance
  • Phenazepam
  • Benzodiazepines
  • Nifoxipam
  • Depressants
  • Meclonazepam
  • Etizolam
  • Diclazepam
  • Desmethylflunitrazepam
  • Desmethyletizolam
  • Adinazolam
  • 3-Hydroxyphenazepam